Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry

Membrane proteins reside in lipid bilayers and are typically extracted from this environment for study, which often compromises their integrity. In this work, we ejected intact assemblies from membranes, without chemical disruption, and used mass spectrometry to define their composition. From Escher...

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Main Authors: Chorev, D, Baker, L, Wu, D, Beilsten-Edmands, V, Rouse, S, Zeev-Ben-Mordehai, T, Jiko, C, Samsudin, F, Gerle, C, Khalid, S, Stewart, A, Matthews, S, Grünewald, K, Robinson, C
格式: Journal article
语言:English
出版: American Association for the Advancement of Science 2018