Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop

<p><strong>Background</strong></p> The use of placebo comparisons for randomised trials assessing the efficacy of surgical interventions is increasingly being considered. However, a placebo control is a complex type of comparison group in the surgical setting and, although po...

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Main Authors: Beard, DJ, Campbell, MK, Blazeby, JM, Carr, AJ, Weijer, C, Cuthbertson, BH, Buchbinder, R, Pinkney, T, Bishop, FL, Pugh, J, Cousins, S, Harris, I, Lohmander, LS, Blencowe, N, Gillies, K, Probst, P, Brennan, C, Cook, A, Farrar-Hockley, D, Savulescu, J, Huxtable, R, Rangan, A, Tracey, I, Brocklehurst, P, Ferreria, ML, Nicholl, J, Reeves, BC, Hamdy, F, Rowley, SCS, Lee, N, Cook, JA
Format: Journal article
Language:English
Published: NIHR Journals Library 2021