Mitochondrial tumour suppressors: a genetic and biochemical update.
Since the discovery 5 years ago that the D-subunit of succinate dehydrogenase (SDHD) can behave as a classic tumour suppressor, other nuclear-encoded mitochondrial proteins (SDHB, SDHC and fumarate hydratase) have been implicated in tumour susceptibility. Mutations in these proteins are principally...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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