Mitochondrial tumour suppressors: a genetic and biochemical update.
Since the discovery 5 years ago that the D-subunit of succinate dehydrogenase (SDHD) can behave as a classic tumour suppressor, other nuclear-encoded mitochondrial proteins (SDHB, SDHC and fumarate hydratase) have been implicated in tumour susceptibility. Mutations in these proteins are principally...
Main Authors: | Gottlieb, E, Tomlinson, I |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2005
|
Similar Items
-
The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.
by: Sieber, O, et al.
Published: (2000) -
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
by: Frezza, C, et al.
Published: (2011) -
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
by: Frezza, C, et al.
Published: (2011) -
Tumour suppressors in liver carcinogenesis.
by: Dufour, J, et al.
Published: (2007) -
Population genetics of tumours.
by: Bodmer, W, et al.
Published: (1996)