Mechanistic and structural study of human aspartate/asparagine-beta-hydroxylase

<p>The 2-oxoglutarate (2OG) dependent oxygenases are a superfamily of enzymes that utilise an Fe(II) cofactor and 2OG co-substrate for the catalysis of oxidative reactions. It is widely considered that an Fe(II)-binding motif comprising two histidine residues and a third acidic residue, thus c...

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Bibliographic Details
Main Author: Brasnett, A
Other Authors: Schofield, C
Format: Thesis
Language:English
Published: 2023
Subjects: