Modulation of the PD-1 pathway by inhibitory antibody superagonists
<p>In metozoans, most of the key events that lead to cell activation and inhibition are controlled by tyrosine phosphorylation. Extracellular signals are transmitted by membrane bound receptors, which have intrinsic kinase activity or themselves recruit intracellular kinases to specialised inh...
Main Author: | Akkaya, B |
---|---|
Other Authors: | Davis, S |
Format: | Thesis |
Language: | English |
Published: |
2012
|
Subjects: |
Similar Items
-
Second generation superagonistic anti-PD-1 antibodies
by: Yu, SY
Published: (2019) -
Inhibitory superagonistic antibodies as novel therapeutics
by: Donat, RF
Published: (2023) -
In vivo characterization of inhibitory anti-PD-1 antibody superagonists
by: Akkaya, B, et al.
Published: (2011) -
Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors
by: Adam P. Curnock, et al.
Published: (2021-10-01) -
Neuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1
by: Julien Rossignol, et al.
Published: (2022-06-01)