Activation of human mucosal-associated invariant T cells induces CD40L-dependent maturation of monocyte-derived and primary dendritic cells

Mucosal-associated invariant T (MAIT) cells are innate T cells that recognize intermediates of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 molecule. It remains unclear whether, in addition to their cytolytic activity that is important in antimicrobial defense, MAIT cells hav...

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Bibliographic Details
Main Authors: Salio, M, Gasser, O, Gonzalez-Lopez, C, Martens, A, Veerapen, N, Gileadi, U, Verter, J, Napolitani, G, Anderson, R, Painter, G, Besra, G, Hermans, I, Cerundolo, V
Format: Journal article
Language:English
Published: American Association of Immunologists 2018