Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications.

Upper- and lower-body fat depots exhibit opposing associations with obesity-related metabolic disease. We defined the relationship between DEXA-quantified fat depots and diabetes/cardiovascular risk factors in a healthy population-based cohort (n = 3,399). Gynoid fat mass correlated negatively with...

Descripció completa

Dades bibliogràfiques
Autors principals:	Pinnick, K, Nicholson, G, Manolopoulos, K, McQuaid, SE, Valet, P, Frayn, K, Denton, N, Min, J, Zondervan, K, Fleckner, J, McCarthy, M, Holmes, C, Karpe, F
Format:	Journal article
Idioma:	English
Publicat:	American Diabetes Association 2014

Ítems similars

Development of an arterio-venous difference method to study the metabolic physiology of the femoral adipose tissue depot.
per: McQuaid, SE, et al.
Publicat: (2010)

Femoral adipose tissue may accumulate the fat that has been recycled as VLDL and nonesterified fatty acids.
per: McQuaid, SE, et al.
Publicat: (2010)

Postprandial triglyceride balance in adipose tissue is largely dependent of LPL action and enhancement of LPL
per: Ruge, T, et al.
Publicat: (2007)

Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis
per: Denton, N, et al.
Publicat: (2018)

Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo
per: Manolopoulos, K, et al.
Publicat: (2012)

Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.
per: Goossens, G, et al.
Publicat: (2006)

Genomics of adipose tissue
per: Pinnick, K, et al.
Publicat: (2014)

Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo.
per: Manolopoulos, K, et al.
Publicat: (2012)

Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.
per: Hodson, L, et al.
Publicat: (2009)

DNA methylation of genes in adipose tissue
per: Pinnick, K, et al.
Publicat: (2011)

DNA methylation of genes in adipose tissue.
per: Pinnick, K, et al.
Publicat: (2011)

Gluteofemoral Fat as a Determinant of Metabolic Health: Differential Adrenergic Regulation of Regional Lipolysis and Adipose Tissue Blood Flow In Vivo
per: Manolopoulos, K, et al.
Publicat: (2010)

Angiotensin II: A major regulator of subcutaneous adipose tissue blood flow in humans
per: Goossens, G, et al.
Publicat: (2005)

Depot-specific and sex-specific secretion of leptin and interleukin 6: higher leptin release in women and lower interleukin-6 release from femoral adipose tissue in vivo
per: Manolopoulos, K, et al.
Publicat: (2013)

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?
per: McQuaid, SE, et al.
Publicat: (2011)

Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans.
per: Pinnick, K, et al.
Publicat: (2012)

Biology of upper-body and lower-body adipose tissue-link to whole-body phenotypes.
per: Karpe, F, et al.
Publicat: (2015)

Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?
per: Hodson, L, et al.
Publicat: (2010)

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.
per: Rantalainen, M, et al.
Publicat: (2011)

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?
per: McQuaid, S, et al.
Publicat: (2011)

The contribution of splanchnic fat to VLDL triglyceride is greater in insulin-resistant than insulin-sensitive men and women: studies in the postprandial state.
per: Hodson, L, et al.
Publicat: (2007)

Regulation of human subcutaneous adipose tissue blood flow
per: Frayn, K, et al.
Publicat: (2014)

Regulation of human subcutaneous adipose tissue blood flow.
per: Frayn, K, et al.
Publicat: (2014)

RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
per: Loh, NY, et al.
Publicat: (2020)

Adipose tissue fatty acid metabolism and cardiovascular disease.
per: Frayn, K, et al.
Publicat: (2005)

Response to Janiszewski et al.
per: Manolopoulos, K, et al.
Publicat: (2010)

Gluteofemoral body fat as a determinant of metabolic health.
per: Manolopoulos, K, et al.
Publicat: (2010)

Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes.
per: Min, J, et al.
Publicat: (2012)

Adipose tissue: a key target for diabetes pathophysiology and treatment?
per: Frayn, K, et al.
Publicat: (2007)

Micro-ribonucleic acid expression profiling and expression quantitative trait loci analysis in human gluteal and abdominal adipose tissue
per: Rantalainen, M, et al.
Publicat: (2010)

Metabolic signatures of human adipose tissue hypoxia in obesity.
per: Hodson, L, et al.
Publicat: (2013)

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.
per: Mattias Rantalainen, et al.
Publicat: (2011-01-01)

Integrative physiology of human adipose tissue.
per: Frayn, K, et al.
Publicat: (2003)

Physical activity and exercise in the regulation of human adipose tissue physiology.
per: Thompson, D, et al.
Publicat: (2012)

The presence of methylation quantitative trait loci indicate a direct genetic influence on the level of methylation in adipose tissue
per: Drong, A, et al.
Publicat: (2011)

Resistance to vasodilatation in adipose tissue: The first stage leading to the metabolic syndrome?
per: Ardilouze, J, et al.
Publicat: (2005)

Adipose tissue and skeletal muscle metabolism in Type 2 diabetes: in vivo effects of rosiglitazone in humans
per: Tan, G, et al.
Publicat: (2002)

Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans.
per: Karpe, F, et al.
Publicat: (1997)

Adipose tissue metabolism.
per: Frayn, K
Publicat: (1989)

Reversible Interconversion of Cortisol and Cortisone in Human Subcutaneous Adipose Tissue and Skeletal Muscle In Vivo
per: Hughes, K, et al.
Publicat: (2010)