Excess mortality following hip fracture: a systematic epidemiological review.

This systematic literature review has shown that patients experiencing hip fracture after low-impact trauma are at considerable excess risk for death compared with nonhip fracture/community control populations. The increased mortality risk may persist for several years thereafter, highlighting the n...

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Main Authors: Abrahamsen, B, van Staa, T, Ariely, R, Olson, M, Cooper, C
Format: Journal article
Language:English
Published: 2009
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author Abrahamsen, B
van Staa, T
Ariely, R
Olson, M
Cooper, C
author_facet Abrahamsen, B
van Staa, T
Ariely, R
Olson, M
Cooper, C
author_sort Abrahamsen, B
collection OXFORD
description This systematic literature review has shown that patients experiencing hip fracture after low-impact trauma are at considerable excess risk for death compared with nonhip fracture/community control populations. The increased mortality risk may persist for several years thereafter, highlighting the need for interventions to reduce this risk.Patients experiencing hip fracture after low-impact trauma are at considerable risk for subsequent osteoporotic fractures and premature death. We conducted a systematic review of the literature to identify all studies that reported unadjusted and excess mortality rates for hip fracture. Although a lack of consistent study design precluded any formal meta-analysis or pooled analysis of the data, we have shown that hip fracture is associated with excess mortality (over and above mortality rates in nonhip fracture/community control populations) during the first year after fracture ranging from 8.4% to 36%. In the identified studies, individuals experienced an increased relative risk for mortality following hip fracture that was at least double that for the age-matched control population, became less pronounced with advancing age, was higher among men than women regardless of age, was highest in the days and weeks following the index fracture, and remained elevated for months and perhaps even years following the index fracture. These observations show that patients are at increased risk for premature death for many years after a fragility-related hip fracture and highlight the need to identify those patients who are candidates for interventions to reduce their risk.
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spelling oxford-uuid:1cbe2c8b-cb23-4e8c-bd20-8d6c5c65f58a2022-03-26T11:07:10ZExcess mortality following hip fracture: a systematic epidemiological review.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1cbe2c8b-cb23-4e8c-bd20-8d6c5c65f58aEnglishSymplectic Elements at Oxford2009Abrahamsen, Bvan Staa, TAriely, ROlson, MCooper, CThis systematic literature review has shown that patients experiencing hip fracture after low-impact trauma are at considerable excess risk for death compared with nonhip fracture/community control populations. The increased mortality risk may persist for several years thereafter, highlighting the need for interventions to reduce this risk.Patients experiencing hip fracture after low-impact trauma are at considerable risk for subsequent osteoporotic fractures and premature death. We conducted a systematic review of the literature to identify all studies that reported unadjusted and excess mortality rates for hip fracture. Although a lack of consistent study design precluded any formal meta-analysis or pooled analysis of the data, we have shown that hip fracture is associated with excess mortality (over and above mortality rates in nonhip fracture/community control populations) during the first year after fracture ranging from 8.4% to 36%. In the identified studies, individuals experienced an increased relative risk for mortality following hip fracture that was at least double that for the age-matched control population, became less pronounced with advancing age, was higher among men than women regardless of age, was highest in the days and weeks following the index fracture, and remained elevated for months and perhaps even years following the index fracture. These observations show that patients are at increased risk for premature death for many years after a fragility-related hip fracture and highlight the need to identify those patients who are candidates for interventions to reduce their risk.
spellingShingle Abrahamsen, B
van Staa, T
Ariely, R
Olson, M
Cooper, C
Excess mortality following hip fracture: a systematic epidemiological review.
title Excess mortality following hip fracture: a systematic epidemiological review.
title_full Excess mortality following hip fracture: a systematic epidemiological review.
title_fullStr Excess mortality following hip fracture: a systematic epidemiological review.
title_full_unstemmed Excess mortality following hip fracture: a systematic epidemiological review.
title_short Excess mortality following hip fracture: a systematic epidemiological review.
title_sort excess mortality following hip fracture a systematic epidemiological review
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AT vanstaat excessmortalityfollowinghipfractureasystematicepidemiologicalreview
AT arielyr excessmortalityfollowinghipfractureasystematicepidemiologicalreview
AT olsonm excessmortalityfollowinghipfractureasystematicepidemiologicalreview
AT cooperc excessmortalityfollowinghipfractureasystematicepidemiologicalreview