Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.

Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.

Proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus (ARC) suppress appetite, and lack of POMC-derived peptides or electrical silencing of POMC neurons causes obesity. ARC POMC neurons are surrounded by nerve terminals containing the wakefulness-promoting peptides orexins/hypocreti...

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Bibliographic Details
Main Authors:	Ma, X, Zubcevic, L, Brüning, J, Ashcroft, F, Burdakov, D
Format:	Journal article
Language:	English
Published:	2007

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