Scenarios for autoimmunization of T and B cells in myasthenia gravis.

We have studied responses in thymoma patients to interferon-alpha and to the acetylcholine receptor (AChR) in early-onset myasthenia gravis (EOMG), seeking clues to autoimmunizing mechanisms. Our new evidence implicates a two-step process: (step 1) professional antigen-presenting cells and thymic ep...

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Detalles Bibliográficos
Autores principales: Shiono, H, Roxanis, I, Zhang, W, Sims, G, Meager, A, Jacobson, L, Liu, J, Matthews, I, Wong, Y, Bonifati, M, Micklem, K, Stott, D, Todd, J, Beeson, D, Vincent, A, Willcox, N
Formato: Journal article
Lenguaje:English
Publicado: 2003