p63 is a promising marker in the diagnosis of unusual skin cancer
<jats:p>Skin cancer is the most common type of cancer worldwide. Ozone depletion and climate changes might cause a further increase in the incidence rate in the future. Although the early detection of skin cancer enables it to be treated successfully, some tumours can evolve and become more ag...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
MDPI
2019
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| _version_ | 1826261973581430784 |
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| author | Smirnov, A Anemona, L Novelli, F Piro, C Annicchiarico-Petruzzelli, M Melino, G Candi, E |
| author_facet | Smirnov, A Anemona, L Novelli, F Piro, C Annicchiarico-Petruzzelli, M Melino, G Candi, E |
| author_sort | Smirnov, A |
| collection | OXFORD |
| description | <jats:p>Skin cancer is the most common type of cancer worldwide. Ozone depletion and climate changes might cause a further increase in the incidence rate in the future. Although the early detection of skin cancer enables it to be treated successfully, some tumours can evolve and become more aggressive, especially in the case of melanoma. Therefore, good diagnostic and prognostic markers are needed to ensure correct detection and treatment. Transcription factor p63, a member of the p53 family of proteins, plays an essential role in the development of stratified epithelia such as skin. In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours.</jats:p> |
| first_indexed | 2024-03-06T19:29:00Z |
| format | Journal article |
| id | oxford-uuid:1ccba027-1781-43da-8f38-dac803fd16e3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:29:00Z |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oxford-uuid:1ccba027-1781-43da-8f38-dac803fd16e32022-03-26T11:07:29Zp63 is a promising marker in the diagnosis of unusual skin cancerJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1ccba027-1781-43da-8f38-dac803fd16e3EnglishSymplectic Elements at OxfordMDPI2019Smirnov, AAnemona, LNovelli, FPiro, CAnnicchiarico-Petruzzelli, MMelino, GCandi, E<jats:p>Skin cancer is the most common type of cancer worldwide. Ozone depletion and climate changes might cause a further increase in the incidence rate in the future. Although the early detection of skin cancer enables it to be treated successfully, some tumours can evolve and become more aggressive, especially in the case of melanoma. Therefore, good diagnostic and prognostic markers are needed to ensure correct detection and treatment. Transcription factor p63, a member of the p53 family of proteins, plays an essential role in the development of stratified epithelia such as skin. In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours.</jats:p> |
| spellingShingle | Smirnov, A Anemona, L Novelli, F Piro, C Annicchiarico-Petruzzelli, M Melino, G Candi, E p63 is a promising marker in the diagnosis of unusual skin cancer |
| title | p63 is a promising marker in the diagnosis of unusual skin cancer |
| title_full | p63 is a promising marker in the diagnosis of unusual skin cancer |
| title_fullStr | p63 is a promising marker in the diagnosis of unusual skin cancer |
| title_full_unstemmed | p63 is a promising marker in the diagnosis of unusual skin cancer |
| title_short | p63 is a promising marker in the diagnosis of unusual skin cancer |
| title_sort | p63 is a promising marker in the diagnosis of unusual skin cancer |
| work_keys_str_mv | AT smirnova p63isapromisingmarkerinthediagnosisofunusualskincancer AT anemonal p63isapromisingmarkerinthediagnosisofunusualskincancer AT novellif p63isapromisingmarkerinthediagnosisofunusualskincancer AT piroc p63isapromisingmarkerinthediagnosisofunusualskincancer AT annicchiaricopetruzzellim p63isapromisingmarkerinthediagnosisofunusualskincancer AT melinog p63isapromisingmarkerinthediagnosisofunusualskincancer AT candie p63isapromisingmarkerinthediagnosisofunusualskincancer |