Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer.

Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer.

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BACKGROUND: Non-muscle invasive (NMI) bladder cancer is characterised by increased expression and activating mutations of FGFR3. We have previously investigated the role of microRNAs in bladder cancer and have shown that FGFR3 is a target of miR-100. In this study, we investigated the effects of hyp...

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Autors principals:	Blick, C, Ramachandran, A, Wigfield, S, McCormick, R, Jubb, A, Buffa, F, Turley, H, Knowles, M, Cranston, D, Catto, J, Harris, A
Format:	Journal article
Idioma:	English
Publicat:	2013

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