Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4

Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4

METTL4 belongs to a subclade of MT-A70 family members of methyltransferase (MTase) proteins shown to mediate <i>N</i><sup>6</sup>-adenosine methylation for both RNA and DNA in diverse eukaryotes. Here, we report that Arabidopsis METTL4 functions as U2 snRNA MTase for <i>...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Luo, Q, Mo, J, Chen, H, Hu, Z, Wang, B, Wu, J, Liang, Z, Xie, W, Du, K, Peng, M, Li, Y, Li, T, Zhang, Y, Shi, X, Shen, W-H, Shi, Y, Dong, A, Wang, H, Ma, J
Μορφή: Journal article
Γλώσσα:English
Έκδοση: Springer Nature 2022
Θέματα:
X-ray crystallography
RNA modification

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