Activation of caspase-3 in permanent and transient brain ischaemia in man.

Animal studies have shown brain ischaemia to cause oxidative damage to DNA and activation of caspase-3, leading to apoptosis. These changes may be exacerbated by reperfusion. To assess caspase-3 activation after transient and permanent brain ischaemia in man, we examined brain tissue from patients w...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Love, S, Barber, R, Srinivasan, A, Wilcock, G
Format: Journal article
Sprache:English
Veröffentlicht: 2000