Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

Genome-wide association studies (GWAS) have identified over two hundred chromosomal loci that modulate risk of coronary artery disease (CAD). The genes affected by variants at these loci are largely unknown and an untapped resource to improve our understanding of CAD pathophysiology and identify pot...

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Bibliographic Details
Main Authors: Lempiäinen, H, Brænne, I, Michoel, T, Tragante, V, Vilne, B, Webb, T, Kyriakou, T, Eichner, J, Zeng, L, Willenborg, C, Franzen, O, Ruusalepp, A, Goel, A, Van Der Laan, S, Biegert, C, Hamby, S, Talukdar, H, Foroughi Asl, H, Cvgenes@Target Consortium, Pasterkamp, G, Watkins, H, Samani, N, Wittenberger, T, Erdmann, J, Schunkert, H, Asselbergs, F, Björkegren, J
Format: Journal article
Language:English
Published: Nature Publishiing Group 2018

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