Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain.

OBJECTIVE: The mechanism of action of anti-B cell therapy in multiple sclerosis (MS) is not fully understood. Here, we compared the effect of anti-CD20 therapy on microglial activation in two distinct focal rat models of MS. METHODS: The effect of anti-CD20 therapy on lesion formation and extralesio...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Anthony, D, Dickens, A, Seneca, N, Couch, Y, Campbell, S, Checa, B, Kersemans, V, Warren, E, Tredwell, M, Sibson, N, Gouverneur, V, Leppert, D
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2014