The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by cytokines released by these cells. Signaling events occurring in the pancreatic beta cells are decisive for their survival or death in diabetes. We have used RNA sequencing (R...

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Bibliographic Details
Main Authors: Eizirik, D, Sammeth, M, Bouckenooghe, T, Bottu, G, Sisino, G, Igoillo-Esteve, M, Ortis, F, Santin, I, Colli, M, Barthson, J, Bouwens, L, Hughes, L, Gregory, L, Lunter, G, Marselli, L, Marchetti, P, McCarthy, M, Cnop, M
Format: Journal article
Language:English
Published: 2012

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