Phospho-regulation of ATOH1 is required for plasticity of secretory progenitors and tissue regeneration

The intestinal epithelium is largely maintained by self-renewing stem cells but with apparently committed progenitors also contributing, particularly following tissue damage. However, the mechanism of, and requirement for, progenitor plasticity in mediating pathological response remain unknown. Here...

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Bibliographic Details
Main Authors: Tomic, G, Morrissey, E, Kozar, S, Ben-Moshe, S, Hoyle, A, Azzarelli, R, Kemp, R, Chilamakuri, C, Itzkovitz, S, Philpott, A, Winton, D
Format: Journal article
Language:English
Published: Elsevier 2018

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