Phospho-regulation of ATOH1 is required for plasticity of secretory progenitors and tissue regeneration
The intestinal epithelium is largely maintained by self-renewing stem cells but with apparently committed progenitors also contributing, particularly following tissue damage. However, the mechanism of, and requirement for, progenitor plasticity in mediating pathological response remain unknown. Here...
Main Authors: | Tomic, G, Morrissey, E, Kozar, S, Ben-Moshe, S, Hoyle, A, Azzarelli, R, Kemp, R, Chilamakuri, C, Itzkovitz, S, Philpott, A, Winton, D |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2018
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