Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141 XCR1 dendritic cells

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141 XCR1 dendritic cells

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Monocyte-derived dendritic cells (moDC) have been widely used in cancer immunotherapy but show significant donor-to-donor variability and low capacity for the cross-presentation of tumour-associated antigens (TAA) to CD8 T cells, greatly limiting the success of this approach. Given recent developmen...

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Bibliographic Details
Main Authors:	Silk, K, Silk, J, Ichiryu, N, Davies, T, Nolan, K, Leishman, A, Carpenter, L, Watt, S, Cerundolo, V, Fairchild, P
Format:	Journal article
Language:	English
Published:	2012

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