A new chemoselective base-mediated protection/deprotection method for aldehydes
A wide range of aldehydes was efficiently protected as pyrrole carbinol derivatives by direct addition of lithium pyrrolate in THF at -78°C. The protection is chemoselective towards aldehydes over ketones and the O-lithiated, O-protonated or O-silylated carbinols may be used to block the aldehyde fr...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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