More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules.

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules.

Enterovirus 71 (HEV71) epidemics in children and infants result mainly in mild symptoms; however, especially in the Asia-Pacific region, infection can be fatal. At present, no therapies are available. We have used structural analysis of the complete virus to guide the design of HEV71 inhibitors. Ana...

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Bibliographic Details
Main Authors:	De Colibus, L, Wang, X, Spyrou, J, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E, Rao, Z, Stuart, D
Format:	Journal article
Language:	English
Published:	Nature Publishing Group 2014

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