Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways.

Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways.

Mucosal Associated Invariant T (MAIT) cells represent an innate T-cell population which can recognize ligands generated by the microbial riboflavin synthesis pathway, presented via the major-histocompatibility-complex (MHC) class I-related molecule MR1. Streptococcus pneumoniae (the 'pneumococc...

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Bibliographic Details
Main Authors: Kurioka, A, van Wilgenburg, B, Javan, R, Hoyle, R, van Tonder, A, Harrold, C, Leng, T, Howson, L, Shepherd, D, Cerundolo, V, Brueggemann, A, Klenerman, P
Format: Journal article
Language:English
Published: Oxford University Press 2017

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