Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways.
Mucosal Associated Invariant T (MAIT) cells represent an innate T-cell population which can recognize ligands generated by the microbial riboflavin synthesis pathway, presented via the major-histocompatibility-complex (MHC) class I-related molecule MR1. Streptococcus pneumoniae (the 'pneumococc...
Main Authors: | Kurioka, A, van Wilgenburg, B, Javan, R, Hoyle, R, van Tonder, A, Harrold, C, Leng, T, Howson, L, Shepherd, D, Cerundolo, V, Brueggemann, A, Klenerman, P |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Oxford University Press
2017
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