A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence.

A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence.

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We have analysed the sequences required for cleavage and polyadenylation in the intronless melanocortin 4 receptor (MC4R) pre-mRNA. Unlike other intronless genes, 3'end processing of the MC4R primary transcript is independent of any auxiliary sequence elements and only requires the core poly(A)...

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Bibliographic Details
Main Authors: Nunes, N, Li, W, Tian, B, Furger, A
Format: Journal article
Language:English
Published: 2010

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