Investigating the inhibitor and substrate diversity of the JmjC histone demethylases

Investigating the inhibitor and substrate diversity of the JmjC histone demethylases

<p>Epigenetic control of gene expression by histone post-translational modifications (PTMs) is a complex process regulated by proteins that can 'read', 'write' or 'erase' these PTMs. The histone lysine demethylase (KDM) family of epigenetic enzymes remove methyl...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч:	Shamo Schiller, R
Бусад зохиолчид:	Kawamura, A
Формат:	Дипломын ажил
Хэл сонгох:	English
Хэвлэсэн:	2016
Нөхцлүүд:	Epigenetics JmjC KDMs

Ижил төстэй зүйлс

Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton
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Genome-wide identification, classification, and expression analysis of the JmjC domain-containing histone demethylase gene family in birch
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Genome-wide identification, classification and expression analysis of the JmjC domain-containing histone demethylase gene family in maize
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Хэвлэсэн: (2019-04-01)

Evolutionary History and Functional Diversification of the <i>JmjC</i> Domain-Containing Histone Demethylase Gene Family in Plants
-н: Shifeng Ma, зэрэг
Хэвлэсэн: (2022-04-01)

Comparative genome-wide identification and characterization of SET domain-containing and JmjC domain-containing proteins in piroplasms
-н: Qindong Liang, зэрэг
Хэвлэсэн: (2024-08-01)

Characterization and Stress Response of the JmjC Domain-Containing Histone Demethylase Gene Family in the Allotetraploid Cotton Species <i>Gossypium hirsutum</i>
-н: Jie Zhang, зэрэг
Хэвлэсэн: (2020-11-01)

JmjC histone demethylases act as chromatin oxygen sensors
-н: Michael Batie, зэрэг
Хэвлэсэн: (2019-07-01)

The Cross Marks the Spot: The Emerging Role of JmjC Domain-Containing Proteins in Myeloid Malignancies
-н: Hans Felix Staehle, зэрэг
Хэвлэсэн: (2021-12-01)

Systematic analysis of JmjC gene family and stress-response expression of KDM5 subfamily genes in Brassica napus
-н: Xinghui He, зэрэг
Хэвлэсэн: (2021-03-01)

Functions and Interactions of Mammalian KDM5 Demethylases
-н: Egor Pavlenko, зэрэг
Хэвлэсэн: (2022-07-01)

Genome-wide identification of the jumonji C domain- containing histone demethylase gene family in wheat and their expression analysis under drought stress
-н: Xinhua Wang, зэрэг
Хэвлэсэн: (2022-08-01)

The emerging roles of lysine-specific demethylase 4A in cancer: Implications in tumorigenesis and therapeutic opportunities
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Inhibitors of JmjC-containing histone demethylases
-н: Wright, M, зэрэг
Хэвлэсэн: (2020)

Investigating the effect of hypoxia on the JmjC histone lysine demethylase KDM4A
-н: Hancock, R
Хэвлэсэн: (2016)

Genome-wide identification and expression analysis of protein arginine methyltransferase and JmjC domain-containing family in apple
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Хэвлэсэн: (2024-05-01)

KDM2 Family Members are Regulated by HIF-1 in Hypoxia
-н: Michael Batie, зэрэг
Хэвлэсэн: (2017-03-01)

JmjC ‐domain‐containing histone demethylases
-н: Højrup, C, зэрэг
Хэвлэсэн: (2019)

Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
-н: Ugo Chianese, зэрэг
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In vitro enzyme assays for JmjC-domain-containing lysine histone demethylases (JmjC-KDMs)
-н: Tarhonskaya, H, зэрэг
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Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms
-н: Michael Batie, зэрэг
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Investigating the substrate selectivity and the inhibitor of the human KDM7 sub-family of JmjC histone lysine demethylases
-н: Zhang, Y
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Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.
-н: Walport, L, зэрэг
Хэвлэсэн: (2016)

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
-н: Louise J. Walport, зэрэг
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A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1.
-н: Schiller, R, зэрэг
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Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution
-н: Katharina E. Bräuer, зэрэг
Хэвлэсэн: (2018-06-01)

Biochemical and cellular studies of the KDM6 sub-family of JmjC histone lysine demethylases
-н: Dunne, K
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Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases.
-н: Woon, E, зэрэг
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The role of histone post-translational modifications in cancer and cancer immunity: functions, mechanisms and therapeutic implications
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Inhibitors of both the N-methyl lysyl- and arginyl- demethylase activities of the JmjC oxygenases
-н: Bonnici, J, зэрэг
Хэвлэсэн: (2018)

Catalysis by the JmjC histone demethylase KDM4A integrates substrate dynamics, correlated motions and molecular orbital control
-н: Ramanan, R, зэрэг
Хэвлэсэн: (2020)

The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations
-н: Hancock, R, зэрэг
Хэвлэсэн: (2017)

JmjC-domain-containing proteins and histone demethylation.
-н: Klose, R, зэрэг
Хэвлэсэн: (2006)

Investigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases
-н: Bhushan, B, зэрэг
Хэвлэсэн: (2018)

Structure–function relationships of human JmjC oxygenases — demethylases versus hydroxylases
-н: Markolovic, S, зэрэг
Хэвлэсэн: (2016)

MoJMJ1, Encoding a Histone Demethylase Containing JmjC Domain, Is Required for Pathogenic Development of the Rice Blast Fungus, Magnaporthe oryzae
-н: Aram Huh, зэрэг
Хэвлэсэн: (2017-04-01)

JmjC domain-containing histone demethylase gene family in Chinese cabbage: Genome-wide identification and expressional profiling.
-н: Fengrui Yin, зэрэг
Хэвлэсэн: (2024-01-01)

Arabidopsis JMJD5/JMJ30 Acts Independently of LUX ARRHYTHMO Within the Plant Circadian Clock to Enable Temperature Compensation
-н: Matthew A. Jones, зэрэг
Хэвлэсэн: (2019-02-01)

Analysis of JmjC Demethylase-Catalyzed Demethylation Using Geometrically-Constrained Lysine Analogues
-н: Langley, G, зэрэг
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Genome-wide identification and expression analysis of the JMJ-C gene family in melon (Cucumis melo L.) reveals their potential role in fruit development
-н: Wuyun Jin, зэрэг
Хэвлэсэн: (2023-12-01)

Heme, A Metabolic Sensor, Directly Regulates the Activity of the KDM4 Histone Demethylase Family and Their Interactions with Partner Proteins
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