Nanoparticle activation methods in cancer treatment
In this review, we intend to highlight the progress which has been made in recent years around different types of smart activation nanosystems for cancer treatment. Conventional treatment methods, such as chemotherapy or radiotherapy, suffer from a lack of specific targeting and consequent off-targe...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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MDPI
2019
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| _version_ | 1797057338961559552 |
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| author | White, B Duan, C Townley, H |
| author_facet | White, B Duan, C Townley, H |
| author_sort | White, B |
| collection | OXFORD |
| description | In this review, we intend to highlight the progress which has been made in recent years around different types of smart activation nanosystems for cancer treatment. Conventional treatment methods, such as chemotherapy or radiotherapy, suffer from a lack of specific targeting and consequent off-target effects. This has led to the development of smart nanosystems which can effect specific regional and temporal activation. In this review, we will discuss the different methodologies which have been designed to permit activation at the tumour site. These can be divided into mechanisms which take advantage of the differences between healthy cells and cancer cells to trigger activation, and those which activate by a mechanism extrinsic to the cell or tumour environment. |
| first_indexed | 2024-03-06T19:34:53Z |
| format | Journal article |
| id | oxford-uuid:1eb169e6-b43b-4f29-9e85-4d20a3c66f07 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:34:53Z |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oxford-uuid:1eb169e6-b43b-4f29-9e85-4d20a3c66f072022-03-26T11:17:52ZNanoparticle activation methods in cancer treatmentJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1eb169e6-b43b-4f29-9e85-4d20a3c66f07EnglishSymplectic Elements at OxfordMDPI2019White, BDuan, CTownley, HIn this review, we intend to highlight the progress which has been made in recent years around different types of smart activation nanosystems for cancer treatment. Conventional treatment methods, such as chemotherapy or radiotherapy, suffer from a lack of specific targeting and consequent off-target effects. This has led to the development of smart nanosystems which can effect specific regional and temporal activation. In this review, we will discuss the different methodologies which have been designed to permit activation at the tumour site. These can be divided into mechanisms which take advantage of the differences between healthy cells and cancer cells to trigger activation, and those which activate by a mechanism extrinsic to the cell or tumour environment. |
| spellingShingle | White, B Duan, C Townley, H Nanoparticle activation methods in cancer treatment |
| title | Nanoparticle activation methods in cancer treatment |
| title_full | Nanoparticle activation methods in cancer treatment |
| title_fullStr | Nanoparticle activation methods in cancer treatment |
| title_full_unstemmed | Nanoparticle activation methods in cancer treatment |
| title_short | Nanoparticle activation methods in cancer treatment |
| title_sort | nanoparticle activation methods in cancer treatment |
| work_keys_str_mv | AT whiteb nanoparticleactivationmethodsincancertreatment AT duanc nanoparticleactivationmethodsincancertreatment AT townleyh nanoparticleactivationmethodsincancertreatment |