The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis.

The role of germline polymorphisms of the T-cell receptor A/D and B loci in susceptibility to ankylosing spondylitis was investigated by linkage studies using microsatellite markers in 215 affected sibling pairs. The presence of a significant susceptibility gene (lambda > or = 1.6) at the TCR...

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Main Authors: Brown, M, Rudwaleit, M, Pile, K, Kennedy, L, Shatford, J, Amos, C, Siminovitch, K, Rubin, L, Calin, A, Wordsworth, B
格式: Journal article
语言:English
出版: 1998