Asymmetric syntheses of (-)-isoretronecanol and (-)-trachelantamidine

Short and concise total asymmetric syntheses of (-)-isoretronecanol and (-)-trachelantamidine are reported. Oxidative cleavage of tert-butyl (S,S,S,Z)-7-[N-benzyl-N-(α-methylbenzyl)amino]cyclohept-3-ene-1- carboxylate, followed by hydrogenolysis promoted in situ cyclisation/reduction, which provided...

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Xehetasun bibliografikoak
Egile Nagusiak: Brambilla, M, Davies, S, Fletcher, A, Roberts, P, Thomson, J
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2014