Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

Breast cancer patients with BRCA1/2‐driven tumors may benefit from targeted therapy. It is not clear whether current BRCA screening guidelines are effective at identifying these patients. The purpose of our study was to evaluate the prevalence of inherited BRCA1/2 pathogenic variants in a large, cli...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Li, J, Wen, W, Eklund, M, Kvist, A, Eriksson, M, Christensen, H, Torstensson, A, Bajalica-Lagercrantz, S, Dunning, A, Decker, B, Allen, J, Luccarini, C, Pooley, K, Simard, J, Dorling, L, Easton, D, Teo, S, Hall, P, Borg, Å, Grönberg, H, Czene, K
Format: Journal article
Sprache:English
Veröffentlicht: Wiley 2018