Distinct glycosylation and functional profile of typhoid vaccine-induced antibodies in a UK challenge study and Nepalese children
Vaccines against typhoid fever have been shown to be safe and effective in field trials. The mechanism through which the vaccines protect remains elusive. Recent data have implicated antibody glycosylation, and specifically afucosylated antibodies, as an important factor in vaccine-induced effector...
Main Authors: | Stockdale, LK, de Haan, N, Hill, J, Johnson, M, Tomic, A, Wuhrer, M, Jones, E, Jin, C, Nouta, J, Koeleman, CAM, Verheul, M, Basnyat, B, Shakya, M, Pant, D, Provstgaard-Morys, S, Pollard, AJ |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2022
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