Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
One function of N-linked glycans is to assist in the folding of glycoproteins by mediating interactions of the lectin-like chaperone proteins calnexin and calreticulin with nascent glycoproteins. These interactions can be prevented by inhibitors of thea-glucosidases, such asN-butyl-deoxynojirimycin...
Main Authors: | Zitzmann, N, Mehta, A, Carrouee, S, Butters, T, Platt, F, McCauley, J, Blumberg, B, Dwek, R, Block, T |
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Format: | Journal article |
Published: |
National Academy of Sciences
1999
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