Examining the statistical properties of fine-scale mapping in large-scale association studies.
Interpretation of dense single nucleotide polymorphism (SNP) follow-up of genome-wide association or linkage scan signals can be facilitated by establishing expectation for the behaviour of primary mapping signals upon fine-mapping, under both null and alternative hypotheses. We examined the inferen...
Main Authors: | Wiltshire, S, Morris, A, Zeggini, E |
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Format: | Journal article |
Language: | English |
Published: |
2008
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