"Zn-link": a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E.

Ribonuclease E is an essential hydrolytic endonuclease in Escherichia coli, and it plays a central role in maintaining the balance and composition of the messenger RNA population. The enzyme is also required for rRNA and tRNA processing. We have shown earlier that the highly conserved catalytic doma...

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Bibliographic Details
Main Authors: Callaghan, A, Redko, Y, Murphy, L, Grossmann, J, Yates, D, Garman, E, Ilag, L, Robinson, C, Symmons, M, McDowall, K, Luisi, B
Format: Journal article
Language:English
Published: 2005