Prolidase deficiency causes spontaneous T cell activation and lupus-like autoimmunity
<p>Prolidase deficiency (PD) is a multisystem disorder caused by mutations in the <em>PEPD</em> gene, which encodes a ubiquitously expressed metallopeptidase essential for the hydrolysis of dipeptides containing C-terminal proline or hydroxyproline. PD typically p...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
American Association of Immunologists
2023
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