Investigating selection on viruses: a statistical alignment approach.

BACKGROUND: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading frame can bias our estimates of neutral mutation rates in another reading frame. Secondly, the high mutation rates we are li...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: de Groot, S, Mailund, T, Lunter, G, Hein, J
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: BioMed Central 2008

Míreanna comhchosúla