Investigating selection on viruses: a statistical alignment approach.

Investigating selection on viruses: a statistical alignment approach.

BACKGROUND: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading frame can bias our estimates of neutral mutation rates in another reading frame. Secondly, the high mutation rates we are li...

书目详细资料
Main Authors:	de Groot, S, Mailund, T, Lunter, G, Hein, J
格式:	Journal article
语言:	English
出版:	BioMed Central 2008

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