Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
Colorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledm...
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Elsevier
2017
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author | Abbott, E Falzone, N Winter, H Greenhalgh, T Kartsonaki, C Craig, A Denis-Bacelar, A Flux, G Sharma, R Vallis, K |
author_facet | Abbott, E Falzone, N Winter, H Greenhalgh, T Kartsonaki, C Craig, A Denis-Bacelar, A Flux, G Sharma, R Vallis, K |
author_sort | Abbott, E |
collection | OXFORD |
description | Colorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledmicrospheres into the arterial blood supply of tumours in the liver. Radioactivity prescription for 90YSIRTis currently based on a body surface area (BSA) formula. The purpose of this study was to conduct a lesion-by-lesion analysis to establish a dose-response relationship. |
first_indexed | 2024-03-06T19:37:16Z |
format | Conference item |
id | oxford-uuid:1f7698c9-d721-44a0-81bf-e98ec36c218a |
institution | University of Oxford |
last_indexed | 2024-03-06T19:37:16Z |
publishDate | 2017 |
publisher | Elsevier |
record_format | dspace |
spelling | oxford-uuid:1f7698c9-d721-44a0-81bf-e98ec36c218a2022-03-26T11:21:59ZDosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:1f7698c9-d721-44a0-81bf-e98ec36c218aSymplectic Elements at OxfordElsevier2017Abbott, EFalzone, NWinter, HGreenhalgh, TKartsonaki, CCraig, ADenis-Bacelar, AFlux, GSharma, RVallis, KColorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledmicrospheres into the arterial blood supply of tumours in the liver. Radioactivity prescription for 90YSIRTis currently based on a body surface area (BSA) formula. The purpose of this study was to conduct a lesion-by-lesion analysis to establish a dose-response relationship. |
spellingShingle | Abbott, E Falzone, N Winter, H Greenhalgh, T Kartsonaki, C Craig, A Denis-Bacelar, A Flux, G Sharma, R Vallis, K Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title | Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title_full | Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title_fullStr | Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title_full_unstemmed | Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title_short | Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
title_sort | dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy |
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