Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy

Colorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledm...

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Main Authors: Abbott, E, Falzone, N, Winter, H, Greenhalgh, T, Kartsonaki, C, Craig, A, Denis-Bacelar, A, Flux, G, Sharma, R, Vallis, K
Format: Conference item
Published: Elsevier 2017
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author Abbott, E
Falzone, N
Winter, H
Greenhalgh, T
Kartsonaki, C
Craig, A
Denis-Bacelar, A
Flux, G
Sharma, R
Vallis, K
author_facet Abbott, E
Falzone, N
Winter, H
Greenhalgh, T
Kartsonaki, C
Craig, A
Denis-Bacelar, A
Flux, G
Sharma, R
Vallis, K
author_sort Abbott, E
collection OXFORD
description Colorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledmicrospheres into the arterial blood supply of tumours in the liver. Radioactivity prescription for 90YSIRTis currently based on a body surface area (BSA) formula. The purpose of this study was to conduct a lesion-by-lesion analysis to establish a dose-response relationship.
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spelling oxford-uuid:1f7698c9-d721-44a0-81bf-e98ec36c218a2022-03-26T11:21:59ZDosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:1f7698c9-d721-44a0-81bf-e98ec36c218aSymplectic Elements at OxfordElsevier2017Abbott, EFalzone, NWinter, HGreenhalgh, TKartsonaki, CCraig, ADenis-Bacelar, AFlux, GSharma, RVallis, KColorectal cancer (CRC) is acommon cause of cancerrelated deaths (12.2% overall mortality, GLOBOCAN 2012 v1.0). Approximately half of CRC patients develop or present with metastasis (mCRC) to the liver. Selective internal radiation therapy (SIRT) involves injection of yttrium-90 (90Y) radiolabelledmicrospheres into the arterial blood supply of tumours in the liver. Radioactivity prescription for 90YSIRTis currently based on a body surface area (BSA) formula. The purpose of this study was to conduct a lesion-by-lesion analysis to establish a dose-response relationship.
spellingShingle Abbott, E
Falzone, N
Winter, H
Greenhalgh, T
Kartsonaki, C
Craig, A
Denis-Bacelar, A
Flux, G
Sharma, R
Vallis, K
Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title_full Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title_fullStr Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title_full_unstemmed Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title_short Dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
title_sort dosimetric analysis of individual liver metastases from colorectal cancer following 90 y microsphere selective internal radiation therapy
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