Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening.
The biparietal diameter of 20 fetuses with spina bifida was measured during pregnancy by ultrasound scanning, mainly in the second trimester. The mean result was 0.83 cm smaller than the value based on 186 unaffected pregnancies at the same gestational ages (P less than 0.001), suggesting that spina...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1980
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| _version_ | 1797057501846306816 |
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| author | Wald, N Cuckle, H Boreham, J Stirrat, G |
| author_facet | Wald, N Cuckle, H Boreham, J Stirrat, G |
| author_sort | Wald, N |
| collection | OXFORD |
| description | The biparietal diameter of 20 fetuses with spina bifida was measured during pregnancy by ultrasound scanning, mainly in the second trimester. The mean result was 0.83 cm smaller than the value based on 186 unaffected pregnancies at the same gestational ages (P less than 0.001), suggesting that spina bifida fetuses are growth retarded. The practical consequence of this finding is that the routine use of ultrasound in pregnancy will increase the sensitivity of AFP screening for open spina bifida at 16 to 18 weeks gestation from 79 per cent as estimated by the UK Collaborative AFP Study to about 90 per cent or more. |
| first_indexed | 2024-03-06T19:37:18Z |
| format | Journal article |
| id | oxford-uuid:1f77f1c2-c9d3-4faa-9a1a-d24a1521c2ad |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:37:18Z |
| publishDate | 1980 |
| record_format | dspace |
| spelling | oxford-uuid:1f77f1c2-c9d3-4faa-9a1a-d24a1521c2ad2022-03-26T11:22:03ZSmall biparietal diameter of fetuses with spina bifida: implications for antenatal screening.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1f77f1c2-c9d3-4faa-9a1a-d24a1521c2adEnglishSymplectic Elements at Oxford1980Wald, NCuckle, HBoreham, JStirrat, GThe biparietal diameter of 20 fetuses with spina bifida was measured during pregnancy by ultrasound scanning, mainly in the second trimester. The mean result was 0.83 cm smaller than the value based on 186 unaffected pregnancies at the same gestational ages (P less than 0.001), suggesting that spina bifida fetuses are growth retarded. The practical consequence of this finding is that the routine use of ultrasound in pregnancy will increase the sensitivity of AFP screening for open spina bifida at 16 to 18 weeks gestation from 79 per cent as estimated by the UK Collaborative AFP Study to about 90 per cent or more. |
| spellingShingle | Wald, N Cuckle, H Boreham, J Stirrat, G Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title | Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title_full | Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title_fullStr | Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title_full_unstemmed | Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title_short | Small biparietal diameter of fetuses with spina bifida: implications for antenatal screening. |
| title_sort | small biparietal diameter of fetuses with spina bifida implications for antenatal screening |
| work_keys_str_mv | AT waldn smallbiparietaldiameteroffetuseswithspinabifidaimplicationsforantenatalscreening AT cuckleh smallbiparietaldiameteroffetuseswithspinabifidaimplicationsforantenatalscreening AT borehamj smallbiparietaldiameteroffetuseswithspinabifidaimplicationsforantenatalscreening AT stirratg smallbiparietaldiameteroffetuseswithspinabifidaimplicationsforantenatalscreening |