Should controls with respiratory symptoms be excluded from case-control studies of pneumonia etiology? Reflections from the PERCH study.

Should controls with respiratory symptoms be excluded from case-control studies of pneumonia etiology? Reflections from the PERCH study.

Many pneumonia etiology case-control studies exclude controls with respiratory illness from enrollment or analyses. Herein we argue that selecting controls regardless of respiratory symptoms provides the least biased estimates of pneumonia etiology. We review 3 reasons investigators may choose to ex...

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Bibliographic Details
Main Authors: Higdon, MM, Hammitt, LL, Knoll, M, Baggett, HC, Brooks, WA, Howie, SRC, Kotloff, KL, Levine, OS, Madhi, SA, Murdoch, DR, Scott, JAG, Thea, DM, Driscoll, AJ, Karron, RA, Park, DE, Prosperi, C, Zeger, SL, O'Brien, KL, Feikin, DR
Format: Journal article
Language:English
Published: Oxford University Press 2017

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