DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.

DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.

The premature human ageing Werner's syndrome is caused by loss or mutation of the WRN helicase/exonuclease. We have recently identified the orthologue of the WRN exonuclease in flies, DmWRNexo, encoded by the CG7670 locus, and showed very high levels of mitotic recombination in a hypomorphic Pi...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Boubriak, I, Mason, P, Clancy, D, Dockray, J, Saunders, R, Cox, L
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2009

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