A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

The voltage-gated potassium channel Kv1.3 plays an apparent dual physiological role by participating in activation and proliferation of leukocytes as well as promoting apoptosis in several types of tumor cells. Therefore, Kv1.3 is considered a potential pharmacological target for immunodeficiency an...

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Những tác giả chính: Capera Aragones, JCA, Pérez-Verdaguer, M, Peruzzo, R, Navarro-Pérez, M, Martínez-Pinna, J, Alberola-Die, A, Morales, A, Leanza, L, Szabó, I, Felipe, A, Capera, J
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications 2021