Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles
The electrophilic fluorination of silylated N,O-heterocycles, prepared from a nitroso-Diels-Alder reaction of silylated dienes, afforded fluorinated 1,2-oxazines with the fluorine substituent on a stereogenic centre in moderate to high diastereoselectivities. The sense and level of diastereocontrol...
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Journal article |
| Γλώσσα: | English |
| Έκδοση: |
2007
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| _version_ | 1826262581431500800 |
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| author | Lam, Y Hopkinson, M Stanway, S Gouverneur, V |
| author_facet | Lam, Y Hopkinson, M Stanway, S Gouverneur, V |
| author_sort | Lam, Y |
| collection | OXFORD |
| description | The electrophilic fluorination of silylated N,O-heterocycles, prepared from a nitroso-Diels-Alder reaction of silylated dienes, afforded fluorinated 1,2-oxazines with the fluorine substituent on a stereogenic centre in moderate to high diastereoselectivities. The sense and level of diastereocontrol were found to be dependent of the substitution pattern of the heterocycle. © Georg Thieme Verlag Stuttgart. |
| first_indexed | 2024-03-06T19:38:28Z |
| format | Journal article |
| id | oxford-uuid:1fd84ecd-3750-4bd3-b2cf-59ed03b44360 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:38:28Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:1fd84ecd-3750-4bd3-b2cf-59ed03b443602022-03-26T11:24:15ZDiastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocyclesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1fd84ecd-3750-4bd3-b2cf-59ed03b44360EnglishSymplectic Elements at Oxford2007Lam, YHopkinson, MStanway, SGouverneur, VThe electrophilic fluorination of silylated N,O-heterocycles, prepared from a nitroso-Diels-Alder reaction of silylated dienes, afforded fluorinated 1,2-oxazines with the fluorine substituent on a stereogenic centre in moderate to high diastereoselectivities. The sense and level of diastereocontrol were found to be dependent of the substitution pattern of the heterocycle. © Georg Thieme Verlag Stuttgart. |
| spellingShingle | Lam, Y Hopkinson, M Stanway, S Gouverneur, V Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title | Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title_full | Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title_fullStr | Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title_full_unstemmed | Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title_short | Diastereoselective fluorination of silylated 1,2-oxazines to access fluorinated N,O-heterocycles |
| title_sort | diastereoselective fluorination of silylated 1 2 oxazines to access fluorinated n o heterocycles |
| work_keys_str_mv | AT lamy diastereoselectivefluorinationofsilylated12oxazinestoaccessfluorinatednoheterocycles AT hopkinsonm diastereoselectivefluorinationofsilylated12oxazinestoaccessfluorinatednoheterocycles AT stanways diastereoselectivefluorinationofsilylated12oxazinestoaccessfluorinatednoheterocycles AT gouverneurv diastereoselectivefluorinationofsilylated12oxazinestoaccessfluorinatednoheterocycles |