Inferring transmission bottleneck size from viral sequence data using a novel haplotype reconstruction method

The transmission bottleneck is defined as the number of viral particles that transmit from one host to establish an infection in another. Genome sequence data have been used to evaluate the size of the transmission bottleneck between humans infected with the influenza virus; however, the methods use...

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Bibliographic Details
Main Authors: Ghafari, M, Lumby, CK, Weissman, DB, Illingworth, CJR
Format: Journal article
Language:English
Published: American Society for Microbiology 2020

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