Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration
Transcriptome deconvolution in cancer and other heterogeneous tissues remains challenging. Available methods lack the ability to estimate both component-specific proportions and expression profiles for individual samples. We present DeMixT, a new tool to deconvolve high-dimensional data from mixture...
Principais autores: | Wang, Z, Cao, S, Morris, J, Ahn, J, Liu, R, Tyekucheva, S, Gao, F, Li, B, Lu, W, Tang, X, Wistuba, I, Bowden, M, Mucci, L, Loda, M, Parmigiani, G, Holmes, C, Wang, W |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Elsevier
2018
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