Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration

Transcriptome deconvolution in cancer and other heterogeneous tissues remains challenging. Available methods lack the ability to estimate both component-specific proportions and expression profiles for individual samples. We present DeMixT, a new tool to deconvolve high-dimensional data from mixture...

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Detalhes bibliográficos
Principais autores: Wang, Z, Cao, S, Morris, J, Ahn, J, Liu, R, Tyekucheva, S, Gao, F, Li, B, Lu, W, Tang, X, Wistuba, I, Bowden, M, Mucci, L, Loda, M, Parmigiani, G, Holmes, C, Wang, W
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2018

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