Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy.
| Main Authors: | , , , |
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| 格式: | Conference item |
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Lippincott, Williams & Wilkins
2017
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| 总结: | Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy. |
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