Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy.
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Format: | Conference item |
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Lippincott, Williams & Wilkins
2017
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_version_ | 1797057701624152064 |
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author | Arroyo Hornero, R Issa, F Hester, J Wood, K |
author_facet | Arroyo Hornero, R Issa, F Hester, J Wood, K |
author_sort | Arroyo Hornero, R |
collection | OXFORD |
description | Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy. |
first_indexed | 2024-03-06T19:40:09Z |
format | Conference item |
id | oxford-uuid:20636a8d-02ae-4bbf-b0da-767d85d775f2 |
institution | University of Oxford |
last_indexed | 2024-03-06T19:40:09Z |
publishDate | 2017 |
publisher | Lippincott, Williams & Wilkins |
record_format | dspace |
spelling | oxford-uuid:20636a8d-02ae-4bbf-b0da-767d85d775f22022-03-26T11:27:21ZModulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:20636a8d-02ae-4bbf-b0da-767d85d775f2Symplectic Elements at OxfordLippincott, Williams & Wilkins2017Arroyo Hornero, RIssa, FHester, JWood, KRegulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy. |
spellingShingle | Arroyo Hornero, R Issa, F Hester, J Wood, K Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title | Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title_full | Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title_fullStr | Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title_full_unstemmed | Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title_short | Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy |
title_sort | modulation of cd27 cd70 co stimulatory pathway may allow for the generation of a more potent human regulatory t cell product for cell therapy |
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