Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy

Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy.

Bibliographic Details
Main Authors: Arroyo Hornero, R, Issa, F, Hester, J, Wood, K
Format: Conference item
Published: Lippincott, Williams & Wilkins 2017
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author Arroyo Hornero, R
Issa, F
Hester, J
Wood, K
author_facet Arroyo Hornero, R
Issa, F
Hester, J
Wood, K
author_sort Arroyo Hornero, R
collection OXFORD
description Regulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy.
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institution University of Oxford
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spelling oxford-uuid:20636a8d-02ae-4bbf-b0da-767d85d775f22022-03-26T11:27:21ZModulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:20636a8d-02ae-4bbf-b0da-767d85d775f2Symplectic Elements at OxfordLippincott, Williams & Wilkins2017Arroyo Hornero, RIssa, FHester, JWood, KRegulatory T cell (Treg) therapy is a promising strategy to promote transplant tolerance and aid in the reduction of immunosuppression. This study aims to identify new strategies to increase potency, stability and specificity of human Tregs to produce an effective clinical therapy.
spellingShingle Arroyo Hornero, R
Issa, F
Hester, J
Wood, K
Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title_full Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title_fullStr Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title_full_unstemmed Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title_short Modulation of CD27/CD70 co-stimulatory pathway may allow for the generation of a more potent human regulatory T cell product for cell therapy
title_sort modulation of cd27 cd70 co stimulatory pathway may allow for the generation of a more potent human regulatory t cell product for cell therapy
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AT hesterj modulationofcd27cd70costimulatorypathwaymayallowforthegenerationofamorepotenthumanregulatorytcellproductforcelltherapy
AT woodk modulationofcd27cd70costimulatorypathwaymayallowforthegenerationofamorepotenthumanregulatorytcellproductforcelltherapy