Semimechanistic pharmacokinetic and pharmacodynamic modeling of piperaquine in a volunteer infection study with Plasmodium falciparum blood-stage malaria
Dihydroartemisinin-piperaquine is a recommended first-line artemisinin combination therapy for Plasmodium falciparum malaria. Piperaquine is also under consideration for other antimalarial combination therapies. The aim of this study was to develop a pharmacokinetic-pharmacodynamic model that might...
Main Authors: | Wattanakul, T, Baker, M, Mohrle, J, McWhinney, B, Hoglund, RM, McCarthy, JS, Tarning, J |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Microbiology
2021
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