Plasma biomarker profile alterations during variable blood storage
A major confounding factor in the discovery of disease-specific molecular signatures is the variability in handling clinical blood samples. Consequently, novel protein markers of diseases have failed the “iron test” of validation and implementation into clinical practice because, in addition to pati...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
American Association for Clinical Chemistry
2016
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| _version_ | 1797057719426875392 |
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| author | Kaisar, M van Dullemen, L Thezenas, M Charles, P Ploeg, R Kessler, B |
| author_facet | Kaisar, M van Dullemen, L Thezenas, M Charles, P Ploeg, R Kessler, B |
| author_sort | Kaisar, M |
| collection | OXFORD |
| description | A major confounding factor in the discovery of disease-specific molecular signatures is the variability in handling clinical blood samples. Consequently, novel protein markers of diseases have failed the “iron test” of validation and implementation into clinical practice because, in addition to patient variability, a range of preanalytical parameters contributes to erroneous results. |
| first_indexed | 2024-03-06T19:40:25Z |
| format | Journal article |
| id | oxford-uuid:2078700d-6f9e-4d0a-b44a-f05901ecac39 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T19:40:25Z |
| publishDate | 2016 |
| publisher | American Association for Clinical Chemistry |
| record_format | dspace |
| spelling | oxford-uuid:2078700d-6f9e-4d0a-b44a-f05901ecac392022-03-26T11:27:46ZPlasma biomarker profile alterations during variable blood storageJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2078700d-6f9e-4d0a-b44a-f05901ecac39Symplectic Elements at OxfordAmerican Association for Clinical Chemistry2016Kaisar, Mvan Dullemen, LThezenas, MCharles, PPloeg, RKessler, BA major confounding factor in the discovery of disease-specific molecular signatures is the variability in handling clinical blood samples. Consequently, novel protein markers of diseases have failed the “iron test” of validation and implementation into clinical practice because, in addition to patient variability, a range of preanalytical parameters contributes to erroneous results. |
| spellingShingle | Kaisar, M van Dullemen, L Thezenas, M Charles, P Ploeg, R Kessler, B Plasma biomarker profile alterations during variable blood storage |
| title | Plasma biomarker profile alterations during variable blood storage |
| title_full | Plasma biomarker profile alterations during variable blood storage |
| title_fullStr | Plasma biomarker profile alterations during variable blood storage |
| title_full_unstemmed | Plasma biomarker profile alterations during variable blood storage |
| title_short | Plasma biomarker profile alterations during variable blood storage |
| title_sort | plasma biomarker profile alterations during variable blood storage |
| work_keys_str_mv | AT kaisarm plasmabiomarkerprofilealterationsduringvariablebloodstorage AT vandullemenl plasmabiomarkerprofilealterationsduringvariablebloodstorage AT thezenasm plasmabiomarkerprofilealterationsduringvariablebloodstorage AT charlesp plasmabiomarkerprofilealterationsduringvariablebloodstorage AT ploegr plasmabiomarkerprofilealterationsduringvariablebloodstorage AT kesslerb plasmabiomarkerprofilealterationsduringvariablebloodstorage |