Regulation of intestinal T cell homeostasis by autophagy
<p>Mice in which the autophagy protein ATG16L1 was selectively ablated in T cells develop spontaneous intestinal inflammation, characterized by loss of Foxp3+ Treg cells and a selective expansion of Gata3+ Th2 cells. This phenotype was most pronounced in the colonic lamina propria. Thus, a lac...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2021
|
| Subjects: |