Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection.

BACKGROUND: A polymorphism in exon 4 (C77G) of CD45 that alters CD45 splicing has been associated with autoimmune and infectious diseases in humans. OBJECTIVE: To investigate the effect of C77G in hepatitis C virus (HCV) infected individuals and study the phenotype and function of peripheral blood m...

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Detalles Bibliográficos
Autores principales: Dawes, R, Hennig, B, Irving, W, Petrova, S, Boxall, S, Ward, V, Wallace, D, Macallan, D, Thursz, M, Hill, A, Bodmer, W, Beverley, P, Tchilian, E
Formato: Journal article
Lenguaje:English
Publicado: 2006